METHOD OF HUMAN BLOOD SERUM TESTING FOR ONCOMARKER MUC1 Russian patent published in 2008 - IPC G01N33/577 

Abstract RU 2338200 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to immunotechniques. Method of human blood serum testing for OncoMarker MUC1 is offered for diagnostics of breast cancer (BC) by direct solid-phase bivalent immune photometric analysis using pair of homogeneous antibodies M3F1/M3B11. Formed antigen-antibody complexes are detected using Mab-peroxidase conjugate followed by introduction of stain TMB, and standard OncoMarker is human fat lactoglobule antigen MUC1. Method allows for primary diagnostics of BC stages II and III and for prediction of secondary process development (relapses), and for efficient therapy in determined diagnosis. Application of declared method allows to detect 56-63% BC patients BC by blood serum analysis.

EFFECT: possibility of primary diagnostics of BC stages II and III and prediction of secondary process development (relapses).

4 ex, 2 tbl, 3 dwg

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RU 2 338 200 C1

Authors

Askerova Elena Valentinovna

Bobreneva Rimma Abramovna

Gavrilova Natal'Ja Andreevna

Rykalina Natal'Ja Vladimirovna

Jurin Vitalij L'Vovich

Dates

2008-11-10Published

2007-06-14Filed