METHOD FOR COLORECTAL CANCER DIAGNOSIS/SCREENING BASED ON SIMULTANEOUS QUANTIFICATION OF PROTEIN NATURE TUMOUR MARKERS, GLYCANS ANTIBODIES, G, A AND M IMMUNOGLOBULINS IN HUMAN BLOOD ON BIOLOGICAL MICROCHIP Russian patent published in 2017 - IPC G01N33/543 G01N33/574 

FIELD: medicine.

SUBSTANCE: method involves the simultaneous quantification of protein nature tumour markers, glycan antibodies, G, A and M immunoglobulins in human blood on a biological microchip. For this purpose, the biochip contains hydrogel elements with immobilized antibodies to protein oncomarkers, hydrogel elements with immobilized glycans, hydrogel elements with immobilized antibodies against human immunoglobulins of G, A, M classes. The change in the level of the analyzed markers in comparison with the level in the serum of healthy donors indicates colorectal cancer. The group of inventions also refers to a biological microchip, which is an array of three-dimensional hydrogel elements.

EFFECT: application of this invention allows colorectal cancer diagnosis, screening, simultaneous quantification of protein markers, antibodies to glycans, G, A and M immunoglobulins in human blood on a biological microchip that allows successive reactions of various types.

8 cl, 5 ex, 5 tbl, 7 dwg