METHOD FOR DIFFERENTIAL DIAGNOSTICS OF PSEUDO-TUBERCULOSIS AND INTESTINAL YERSINIOSIS AND DIAGNOSTIC SET FOR ITS REALISATION Russian patent published in 2008 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: determine specific antibodies to activators of diseases in blood serum of the patient using the method of solidphase enzyme multiplied immunoassay where as antigenes are used in one stage two species-specific pore-forming proteins outside membranes (NM) Y. pseudotuberculosis and from Y. enterocolitica. As diagnostic titres in EIA delutions of serum 1:800 for porin NM are accepted. pseudotuberculosis and 1:1600 for porin NM Y.enterocolitica. The diagnostic set on a pseudotuberculosis and intestinal yersiniosis contains a tablet with the immobilized antigens - species-specific proteins-porins of external membrane Y. pseudotuberculosis and Y. enterocolitica, samples control (positive and negative) blood sera and the second common-species antibodies, capacity with ready for the use inactivating and stop reagents, substrate and buffer systems.

EFFECT: possibility to carry out differential diagnostics of pseudotuberculosis from intestinal yersiniosis and to tap cases of the admixed form of yersuniosal infection.

3 dwg, 1 ex, 2 cl