TREATMENT METHOD OF MASSIVE SUBMACULAR HEMORRHAGES Russian patent published in 2008 - IPC A61F9/07 A61K38/43 A61K38/49 A61P27/02 

FIELD: medicine; ophthalmology.

SUBSTANCE: subtotal vitrectomy is carried out. After excision of a hyaloid, retinotomy of hemorrhage is carried out and vitreal cavity is filled with air. On the retina in the hemorrhage dimension recombinant prourokinases "gemaza" solution is injected in the amount of 0.3-0.5 ml 1500-2000 ME for 15-20 minutes and liquid blood fraction is evacuated from under the retina. The rest of the preparation is washed away. In case of incomplete excision of blood from under the retina, the vitreal cavity is filled with air again and recombinant prourokinases is repeatedly injected in the same volume of 500-1000 ME. Air is replaced by aeriform perfluorineorganic bond. After the operation the patient is placed in "on back" position for 2 hours, and then in "face downwards" position for 1-3 days. The method allows to carry out valid and accelerated fibrinous clot lysis which makes a basis of hemorrhage.

EFFECT: termination of mechanical fibrin influence and liquidation of toxic influence of decomposition product of formulated blood elements on retina neuroepithelium and pigmental epithelium with minimisation of retina mechanical trauma during surgical intervention.

2 cl, 2 dwg, 1 ex