IN VITRO EXAMINATION METHOD FOR EARLY PHARMACOCYTOKINETICS OF PHARMACEUTICAL PREPARATIONS Russian patent published in 2008 - IPC G01N33/15 G01N21/64 

Abstract RU 2342654 C1

FIELD: medicine; pharmacology.

SUBSTANCE: invention relates to examination and analysis of interaction between pharmaceutical preparations and living cell cultures, using scanning optical confocal microscopy, particularly to examination of entry, accumulation and distribution pharmacocytokinetics of fluorescent dye marked pharmaceutical in living cells. Applied result consists in widening field of utilisation, and is achieved by the method proposed, based on vital confocal cells scanning, treated with the pharmaceutical, accompanied with metabolic changes dynamics analysis and living cells structure condition, affected by the pharmaceutical taken in and distributed.

EFFECT: widening field of utilisation.

2 ex, 5 dwg

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RU 2 342 654 C1

Authors

Filinova Elena Jur'Evna

Anashkina Ekaterina Nikolaevna

Dates

2008-12-27Published

2007-04-10Filed