SOLID DOSED OUT FORMS INCLUDING FIBRAT AND STATIN Russian patent published in 2009 - IPC A61K9/16 A61K9/20 A61K31/216 A61K31/22 A61K47/44 A61K9/48 A61J3/02 A61K47/02 

Abstract RU 2343905 C2

FIELD: medicine; pharmacology.

SUBSTANCE: invention includes as active substances one or several fibrates and one or several statins or their pharmaceutically comprehensible salt, in carrier chosen from group, consisting of i) admixtures of polyethyleneglycol and poloxamer in the ratio from 2:1 to 3:1 and with the subsequent dispersion on lactose, ii) glyceryl monostearate with the subsequent spraying on lactose or on an admixture of lactose and hydroxypropymethylcellulose; and iii) polyethyleneglycol, with subsequent spraying on Aeroperl. Besides, the invention concerns firm dosed out forms including specified material and way of their obtaining.

EFFECT: possibility to establish suitable biological availability of both active ingredients at peroral insertion.

56 cl, 15 tbl, 15 ex

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RU 2 343 905 C2

Authors

Khol'M Per

Norling Tomas

Dates

2009-01-20Published

2004-10-01Filed