PRODUCTION METHOD OF LOW-WATER-SOLUBLE HARD MATERIALS BASED ON CARBOXYL-CONTAINING POLYSACCHARIDES MODIFIED WITH AMINOSALICYLIC ACID Russian patent published in 2009 - IPC A61K47/48 A61K31/734 A61K31/726 C08B37/04 A61L15/28 

FIELD: chemistry.

SUBSTANCE: used are films made of glycosaminoglycan conjugates with 4- or 5-aminosalicylic acids or alginate conjugates with 4- or 5-aminosalicylic acids or intermixed conjugates or mixed conjugates and at least one polymer chosen from group including carboxymethyl cellulose, glycosaminoglycan, alginate, gelatine, albumin with salicylate content not less than 50%. Specified mixtures are treated with 2-20% iron (III) chloride solution at room temperature within 1-5 minutes. Surface complex lowers water- and biological liquids solubility of the film.

EFFECT: prolonged of biomaterial activity is provided.

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