FIELD: chemistry, pharmaceutics.
SUBSTANCE: described is application of sulfonic acids and their derivatives of formula (I) and pharmaceutically acceptable salts of said compounds (see radical values in invention formula) for obtaining medication for inhibition of human PMN chemotaxis, induced by IL-8 and sulfonic acids and their derivatives of formula (I). Described are three methods of obtaining of the said compounds and pharmaceutical composition based on them.
EFFECT: compounds of formula (I) possess inhibiting activity of human PMN chemotaxis.
11 cl, 2 tbl, 6 ex
Title | Year | Author | Number |
---|---|---|---|
(R)-ARYLALKYLAMINO DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | 2006 |
|
RU2458051C2 |
2-ARYLACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | 2004 |
|
RU2356887C2 |
2-ARYLPROPIONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEREOF | 2002 |
|
RU2317075C2 |
(R)-2-ARYLPROPIONIC ACID OMEGA-AMINOALKYLAMIDE QUATERNARY AMMONIUM SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEREOF | 2002 |
|
RU2291857C2 |
DERIVATIVES OF 2-IMINOPYRROLIDINE | 2002 |
|
RU2270192C2 |
AMIDINES AND THEIR DERIVATIVE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF | 2004 |
|
RU2375346C2 |
HETEROBICYCLIC DERIVATIVES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION | 1995 |
|
RU2170737C2 |
NOVEL INDOLINE COMPOUND AND ITS USING IN MEDICINE | 2003 |
|
RU2318808C2 |
(R)-2-ARYLPROPIONAMIDES USEFUL IN INHIBITION OF IL-8-INDUCED CHEMOTAXIS OF NEUTROPHILES, METHOD AND INTERMEDIATE COMPOUNDS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION INHIBITING INTERLEUKIN-8-INDUCED CHEMOTAXIS OF NEUTROPHILES | 2001 |
|
RU2273630C2 |
INDOLIZINE DERIVATIVES, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF INHIBITION OF ACTIVITY OF TESTOSTERONE-5α-REDUCTASE | 1992 |
|
RU2120942C1 |
Authors
Dates
2009-01-27—Published
2004-03-11—Filed