ANTIBODY AGAINST TUMOR-SPECIFIC ANTIGENS AS TARGET Russian patent published in 2009 - IPC C07K16/18 C07K16/32 A61K39/395 A61P35/00 

FIELD: chemistry, biochemistry.

SUBSTANCE: claimed invention relates to field of biotechnology and immunology. Claimed is monoclonal antibody specific to human oculospanin, possessing cytotoxic activity with respect to human cancer cells. In one of versions antibody is obtained from mouse hybridome O3B8-2C9-4F3, FERM BP-08627. Described is set for cancer detection based on, at least, said antibody and second, specific to it, antibody. Described is pharmaceutical composition for treatment of cancer, whis cells express oculospanin, and application of antibody for manufacturing medication for treatment of cancer, whose cells express oculospanin. Use of invention ensures highly-specific antibodies to human oculospanin, which can find application for diagnostics of tumors, expressing human oculospanin.

EFFECT: ensuring highly-specific antibodies to human oculospanin, which can find application for diagnostics of tumors, expressing human oculospanin.

17 cl, 5 dwg, 10 ex