FIELD: medicine; pharmacology.
SUBSTANCE: composition contains, essentially anhydrous ordered (adhesive) mixture of, at least, one pharmaceutically active agent in the form of microparticles linked to surface of carrier particles which are essentially greater than those of the active agent or agents, and, essentially are water insoluble or poor soluble, in a combination with the agent enabling bioadhesion and/mucoadhesion, linked to surface of specified carrier particles. The composition, mainly, is used for sublingual or intranasal introduction. Besides, the invention refers to method of composition preparation.
EFFECT: improved bioadhesive properties, fast release of active substance.
31 cl, 1 dwg, 1 tbl, 1 ex
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Authors
Dates
2009-02-10—Published
2004-01-15—Filed