FIELD: medicine; pharmacology.
SUBSTANCE: invention represents combination and method of prevention or treatment of prostate cancer using either vitamin E, or derivatives of vitamin E, or analogues of vitamin E and selenium, or selenium salt, or selenium derivative, in bond or free form, separately or combined with traditional therapy. Besides, the present invention presents composition and method for prevention or treatment of prostate cancer in mammals using either vitamin E, or derivatives of vitamin E, or analogues of vitamin E and selenium, of selenium salt, or selenium derivatives, in bond or free form, separately or combined with traditional therapy, by increasing intracellular content of p21 and/or p27. Combination of vitamin E, or derivatives of vitamin E, or analogues of vitamin E and selenium, or selenium salt, or selenium derivative, bond or free form possesses synergetic action and increase T-cell level, inhibits formation of protein complexes cyclin-CDK.
EFFECT: higher efficiency of composition.
31 cl, 23 dwg
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