DERIVATIVE OF CYCLIC AMINE, CONTAINING HETEROARYL CYCLE Russian patent published in 2009 - IPC C07D211/72 C07D401/06 C07D401/14 C07D405/06 C07D409/06 C07D413/06 C07D417/06 A61K31/4025 A61K31/445 A61K31/4523 A61K31/4525 A61K31/4535 A61K31/4545 A61K31/4709 A61P7/02 

Abstract RU 2346935 C2

FIELD: chemistry.

SUBSTANCE: invention concerns compounds with inhibition effect on thrombocyte aggregation, their pharmaceutically acceptable salts, particularly compounds of general formula (I) (where R1 is C1-C6 alkyl etc., R2 is hydrogen, C2-C7 alkanoyl, C7-C11 arylcarbonyl, group of formula R4-(CH2)1- etc., R3 is C6-C10 aryl etc., X1, X2, X3, X4 and X5 are independently hydrogen, halogen etc., and n is an integer from 0 to 2), its pharmaceutically acceptable salts. Invention claims pharmaceutical compositions inhibiting thrombocyte activation and containing claimed compounds as agent.

EFFECT: obtaining compounds applicable as media of prevention and treatment of diseases related to thrombo- or embologenesis.

26 cl, 272 ex, 8 tbl

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RU 2 346 935 C2

Authors

Kimura Tomio

Tanaka Naoki

Sugidati Atsukhiro

Konosu Tosijuki

Dates

2009-02-20Published

2004-11-26Filed