FIELD: chemistry.
SUBSTANCE: invention concerns compounds with inhibition effect on thrombocyte aggregation, their pharmaceutically acceptable salts, particularly compounds of general formula (I) (where R1 is C1-C6 alkyl etc., R2 is hydrogen, C2-C7 alkanoyl, C7-C11 arylcarbonyl, group of formula R4-(CH2)1- etc., R3 is C6-C10 aryl etc., X1, X2, X3, X4 and X5 are independently hydrogen, halogen etc., and n is an integer from 0 to 2), its pharmaceutically acceptable salts. Invention claims pharmaceutical compositions inhibiting thrombocyte activation and containing claimed compounds as agent.
EFFECT: obtaining compounds applicable as media of prevention and treatment of diseases related to thrombo- or embologenesis.
26 cl, 272 ex, 8 tbl
Title | Year | Author | Number |
---|---|---|---|
CYCLIC AMINE DERIVATIVE CONTAINING SUBSTITUTED ALKYL GROUP | 2006 |
|
RU2382771C2 |
NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME FOR TREATMENT OF INFLAMMATORY DISORDERS | 2014 |
|
RU2675818C2 |
MORPHOLINE TYPE CINNAMIDE DERIVATIVE | 2006 |
|
RU2381225C1 |
2-PYRIDONE DERIVATIVES | 2010 |
|
RU2551847C2 |
CYCLIC AMINE DERIVATIVES, OBTAINMENT METHODS, AND PHARMACEUTICAL COMPOSITIONS THEREOF | 2004 |
|
RU2392270C2 |
HETEROCYCLIC COMPOUNDS | 2006 |
|
RU2383539C2 |
SPIROCYCLIC AMINE DERIVATIVES AS S1P MODULATORS | 2011 |
|
RU2602800C2 |
PIPERIDINE DERIVATIVES | 2011 |
|
RU2554353C2 |
5-SUBSTITUTED INDAZOLE AS KINASE INHIBITORS | 2008 |
|
RU2487873C2 |
PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND | 2017 |
|
RU2739983C2 |
Authors
Dates
2009-02-20—Published
2004-11-26—Filed