FIELD: chemistry.
SUBSTANCE: invention relates to compounds of formula
or
or to their pharmaceutically acceptable salts, where ring A, R2, R3, R4 and X are as defined in the description. The disclosed compounds are useful as 11βHSD1 inhibitor. The invention also relates to a pharmaceutical composition, an agent for treating or preventing pathology related to glucocorticoids, a 11βHSD1 inhibitor containing the disclosed compound or its pharmaceutically acceptable salt, and use of the disclosed compounds.
EFFECT: compounds are highly effective.
40 cl, 48 tbl, 191 ex
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Authors
Dates
2010-03-10—Published
2006-06-08—Filed