FUNCTIONALLY RECONSTRUCTED ADJUVANT-CONTAINING VIRUS MEMBRANES Russian patent published in 2009 - IPC A61K39/39 A61K9/133 A61K39/12 A61P31/12 

Abstract RU 2348428 C2

FIELD: medicine; biotechnologies.

SUBSTANCE: substance of invention involved reconstructed virus membrane with lipid bilayer containing fused virus protein and amphiphilic adjuvant represented with lipopeptide. Further invention refers to production procedures of reconstructed virus membranes manifesting fused membrane activity, that are lipid bilayer membranes preferably containing natural virus lipids, fused virus protein, optionally, one or more additional antigens and amphiphilic adjuvants. Besides invention refers to pharmaceutical compositions containing these reconstructed virus membranes.

EFFECT: intensified immune response.

13 cl, 6 ex, 1 tbl, 10 dwg

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RU 2 348 428 C2

Authors

Stegmann Antonius Jokhannes Khendrikus

Vilskhut Jan Kristian

Van Berkum Jokhannes Khenrikus Gerardus

Dates

2009-03-10Published

2004-06-18Filed