FIELD: pharmaceutics.
SUBSTANCE: vaccine composition, a method for reducing a population of immunosuppressive cells in a mammal, and a method of enhancing an immune response in a mammal. Characterized vaccine composition comprises a cationic lipid and a therapeutic factor, which is GM-CSF. Moreover, the composition is in a dose sufficient to reduce the population of suppressor cells of myeloid origin in the subject.
EFFECT: inventions can reduce immunosuppressive cells to improve immune response in mammals and can be used in medicine.
22 cl, 4 dwg, 5 ex
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