STIMULATION OF IMMUNE RESPONSE BY ENANTIOMERS OF CATIONIC LIPIDS Russian patent published in 2014 - IPC A61K31/23 A61K31/231 A61K31/232 A61P37/04 A61K39/00 A61P35/00 A61P31/00 

Abstract RU 2530555 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed is a group if inventions: a pharmaceutical composition, containing immunologically active enantiomer of a component of the cationic lipid R-DOTAP or S-DOTAP, a method of applying the said enantiomer for induction of an immunostimulating adjuvant effect in the immune system, a method of inducing immune response in a patient with applying thereof and a method of treatment or prevention of a disease in the patient by induction of the immunostimulating adjuvant effect by the lipid.

EFFECT: R-DOTAP and S-DOTAP induced production of cytokines IL-2, IL-8, IL-12, chemokines CCL-5, CCL-19 and tumour regression in mice.

23 cl, 15 dwg, 8 ex

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RU 2 530 555 C2

Authors

Vasievich Ehlizabet Ehnn

Chehn' Vehjsju

Toni Kenja

Konn Gregori

Bedu-Addo Frehnk

Khuang Lif

Dates

2014-10-10Published

2009-04-14Filed