FIELD: chemistry.
SUBSTANCE: invention concerns compound of formula (I) where Ry is , or its pharmaceutically acceptable salts. These compounds have phosphodiesterase (PDE) inhibition effect, particularly for PDE-4. Additionally invention claims application of compound of the formula (I) or its pharmaceutically acceptable salt in manufacturing of medicine for treatment and/or prevention of cognitive ability depression or disorder of humans, e.g. of chronic neurological disorder, such as Alzheimer's disease.
EFFECT: enhanced efficiency of composition and treatment method.
17 cl, 21 tbl, 191 ex
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Authors
Dates
2009-03-10—Published
2003-12-19—Filed