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2 542 994

(13)

(51)

IPC

C07D405/12(2006-01-01)

C07D405/14(2006-01-01)

C07D401/12(2006-01-01)

C07D403/12(2006-01-01)

C07D403/14(2006-01-01)

C07D211/96(2006-01-01)

C07D213/64(2006-01-01)

C07D231/56(2006-01-01)

C07D235/26(2006-01-01)

C07D417/14(2006-01-01)

C07D249/18(2006-01-01)

A61K31/416(2006-01-01)

A61K31/427(2006-01-01)

A61K31/4427(2006-01-01)

A61K31/4184(2006-01-01)

A61K31/4192(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2012127760/04, 2010-06-01

(24)

Start date

2010-06-01

(22)

Actual filing date

2010-06-01

(45)

Published

2015-02-27

(72)

Inventor

Branko MilanDin KhunDouehrti Dzhordzh A.Ehlmor Stiven V.Khasvol'D LizaKheksamer LauraKanzer AaronMantej Robert A.Makklellan Uill'Jam Dzh.Park Chang Kh.Park Chehol-MinPetros Ehndrju M.Sun SjaokhunSauehrs Ehndrju Dzh.Sallivan Dzherard M.Tao Chzhi-FuVan Gari T.Van LehVan SiluUehndt Majkl D.Khansen Todd M.

(73)

Holder

Ehbbvi Ink.

BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR TREATING CANER AND IMMUNE DISEASES Russian patent published in 2015 - IPC C07D405/12 C07D405/14 C07D401/12 C07D403/12 C07D403/14 C07D211/96 C07D213/64 C07D231/56 C07D235/26 C07D417/14 C07D249/18 A61K31/416 A61K31/427 A61K31/4427 A61K31/4184 A61K31/4192 A61P35/00

Abstract RU 2542994 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to specific compounds or to their therapeutically acceptable salt presented in the patent claim and representing sulphonyl benzamide derivatives. The invention also refers to a pharmaceutical composition inhibiting the activity of anti-apoptotic proteins of the family Bcl-2, containing an excipient and an effective amount of a specific sulphonyl benzamide derivative.

EFFECT: sulphonyl benzamide derivatives inhibiting the activity of anti-apoptotic Bcl-2 proteins.

2 cl, 3 tbl, 558 ex

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RU 2 542 994 C2

Authors

Branko Milan

Din Khun

Douehrti Dzhordzh A.

Ehlmor Stiven V.

Khasvol'D Liza

Kheksamer Laura

Kanzer Aaron

Mantej Robert A.

Makklellan Uill'Jam Dzh.

Park Chang Kh.

Park Chehol-Min

Petros Ehndrju M.

Sun Sjaokhun

Sauehrs Ehndrju Dzh.

Sallivan Dzherard M.

Tao Chzhi-Fu

Van Gari T.

Van Leh

Van Silu

Uehndt Majkl D.

Khansen Todd M.

Dates

2015-02-27—Published

2010-06-01—Filed