CCR5 EXPRESSION SUPRESSION COMPOSITIONS AND METHODS OF APPLICATION THEREOF Russian patent published in 2009 - IPC A61K31/17 A61K31/436 A61K31/337 A61K31/513 A61K31/7072 A61K31/355 A61P31/18 

Abstract RU 2353357 C2

FIELD: medicine.

SUBSTANCE: composition contains the compound blocking the cyclic state G1, and the antiviral agent that inhibits or reduces HIV penetration into mononuclear cells. The compound blocking the cyclic state G1 is chosen from the group consisting of sodium butyrate, afidicoline, olomucine, roscovitine, tocopherols, tocotrienols, hydroxyurea and rapamycine.

EFFECT: invention ensures reducing receptor site number for HIV penetration into T-cages and increasing in antiviral agent activity.

14 cl, 9 dwg, 9 ex

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RU 2 353 357 C2

Authors

Redfild Robert

Amoroso Ehntoni

Dehvis Ml. Charl'Z Eh.

Ehredia Alonso

Dates

2009-04-27Published

2004-05-17Filed