FIELD: veterinary medicine.
SUBSTANCE: invention is related to veterinary immunology. Method includes introduction of investigated immunomodulator and assessment of immune status. At that PPD-tuberculin is injected to mammals subcutaneously in dose of 1.3-1.8 ml per animal. Then after 3-5 days immunomodulator is injected per 1 kg of animal weight in 0.2-1 ml physiological solution. After 7-10 days BCG vaccine is injected intracutaneously. After 30-35 days after immunisation virulent culture M. bovis is injected subcutaneously in dose of 0.0001 mg, and after 30-35 days postmortem study of slaughtered animals is carried out. Assessment of immune status is carried out by index of protection: from 100% to 67% - high capacity of immunomodulator, 66-43% - medium, from 42% - low.
EFFECT: method makes it possible to increase accuracy of assessment with reduction of material expenses.
2 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREPARING SPECIFIC IMMUNOMODULATOR | 2007 |
|
RU2366455C2 |
| METHOD OF OBTAINING SPECIFIC IMMUNOMODULATOR | 2011 |
|
RU2478399C2 |
| METHOD OF SPECIFIC PREVENTION OF TUBERCULOSIS | 2013 |
|
RU2562550C2 |
| METHOD FOR OBTAINING A SPECIFIC IMMUNOMODULATOR | 2021 |
|
RU2764467C1 |
| METHOD FOR SUPPRESSION OF INCREASED SENSITIVITY OF ANIMALS WITH THE HELP OF TUBERCULIN OR MALEINE INJECTION | 0 |
|
SU1825630A1 |
| METHOD FOR TREATING PULMONARY TUBERCULOSIS AT PREDOMINANTLY PRODUCTIVE TYPE OF TISSUE REACTION | 2000 |
|
RU2204409C2 |
| IMMUNOMODULATING DRUG | 1996 |
|
RU2112543C1 |
| METHOD FOR PREVENTING TUBERCULOSIS | 2004 |
|
RU2266753C1 |
| METHOD OF DIFFERENTIATION OF M. AVIUM SUBSP. PARATUBERCULOSIS FROM OTHER TYPES OF MYCOBACTERIA ON GUINEA PIGS SENSITIZED WITH THESE TYPES OF MYCOBACTERIA | 2022 |
|
RU2800320C1 |
| METHOD FOR SENSITIZING GUINEA PIGS WITH MYCOBACTERIA IN ADJUVANT FOR ASSESSING SENSITIZING PROPERTIES OF MYCOBACTERIA | 2023 |
|
RU2817163C1 |
