FIELD: chemistry.
SUBSTANCE: invention concerns novel compounds of the formula I and their pharmaceutically acceptable salts. Claimed compounds display PPAR agonistic effect. In the general formula I
A is O; X is a link or CH2; R1 is selected out of C1-C3alkyl; each R4 is independently selected out of group including halogen or -OC1-C3alkyl, where -OC1-C3alkyl can be optionally substituted by 1-3 F; each R5 is independently selected out of group including F, CI; R6 is selected out of group including C2-C5alkyl and -CH2cyclopropyl; m is 0; n is integer 1-2; p is integer 0-1.
EFFECT: pharmaceutical composition including claimed compound as active component.
11 cl, 1 tbl, 10 ex
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Authors
Dates
2009-05-20—Published
2005-01-18—Filed