FIELD: chemistry.
SUBSTANCE: invention relates to protein tyrosine phosphatase 1B inhibitors of the given formula 
which are suitable for treating diabetes type 2 and cancer, or pharmaceutically acceptable salts thereof, in which X is selected from CH and N; R1 is selected from C1-3alkyl, optionally substituted with 1-3 halogens or one -OH, -CN, -C(=O)H, -C(=O)C1-3alkyl group, -HC=NOH, -(CH3)C=NOH, -HC=NOC1-3alkyl, -(CH3)C=NOC1-3alkyl, -C(=O)OC1-3alkyl, -C(=O)NHR6, -CH=CH-phenyl, in which phenyl is substituted with -C(=O)OH; R3 is a halogen; R6 is selected from H, C1-3alkyl, phenyl, and CH2-phenyl, where phenyl in both cases is optionally substituted with a halogen.
EFFECT: obtaining novel biologically active compounds for treating diabetes type 2 and cancer, as well as pharmaceutical compositions based thereon.
10 cl, 2 tbl, 9 ex
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