FIELD: biology.
SUBSTANCE: present invention relates to devices for carrying out biotechnological process, in particular, for growing tissue cells and microorganisms in microgravity conditions and can be used in space biotechnology. The bioreactor has a hollow cylindrical body, the ends of which are closed by removable discs, a system for feeding and outlet of culture medium, aerating gas and removal of target product and products of metabolism of cells or microorganisms, unit for controlling and monitoring the culturing process. Inside the cylindrical body and coaxial with it, there is an immovable cylindrical partition wall. Inside the partition wall a movable cylindrical partition wall is fitted on an axis with possibility of rotating, forming coaxially arranged axial, inner and outer circular channels. An impeller of the activator of a circulating stream of gas from the axial to the inner circular channel and back with its rotation actuator is on a shaft with the end of the housing in front of immovable and movable cylindrical partition walls. An immovable swirler of the gas stream in the axial channel is put on the axis of the movable cylindrical partition wall on the other end of the housing. At the ends, the cylindrical movable partition wall has mouth pieces with circular shoulders for creating a gas-storage circular cavity on its inner side. In line with the immovable cylindrical partition wall and to its ends are fixed flanges with circular cone-shaped elements, fitted with clearance from the mouth pieces of the movable cylindrical partition wall. In the inner circular channel between the movable and immovable cylindrical partition walls, there are blades, made in form of an Archimedes screw and fixed to the outer surface of the movable partition wall. The aerator of the system for inlet and outlet of aeration gas has perforated pipe-shaped elements, uniformly arranged near the immovable cylindrical partition wall with clearance from its inner surface.
EFFECT: increased output of the culturing process and improved mass-exchange characteristics.
4 cl, 2 dwg
Title | Year | Author | Number |
---|---|---|---|
VORTEX BIOREACTOR | 2011 |
|
RU2538170C1 |
BIOREACTOR AND METHOD OF CULTURING PHOTOSYNTHESISING MICROORGANISMS USING SAID BIOREACTOR | 2008 |
|
RU2471863C2 |
BIOREACTOR | 2004 |
|
RU2299903C2 |
LABORATORY MULTI-PLATFORM GAS VORTEX BIOREACTOR | 2021 |
|
RU2763318C1 |
APPARATUS FOR SUSPENSION CULTIVATION OF CELLS OF TISSUES AND MICROORGANISMS | 1998 |
|
RU2135579C1 |
APPARATUS FOR SUSPENSION CULTIVATION OF TISSUE CELLS OR MICROORGANISMS | 1992 |
|
RU2099413C1 |
0 |
|
SU1779690A1 | |
DEVICE FOR GROWING TISSUE CELLS OR MICROORGANISMS IN WEIGHTLESSNESS CONDITIONS | 2007 |
|
RU2355752C1 |
APPARATUS FOR SUSPENSION CULTIVATION OF TISSUE OR MICROORGANISM CELLS | 2008 |
|
RU2363729C1 |
REACTOR FOR PERFORMANCE OF BIOTECHNOLOGICAL PROCESSES UNDER CONDITIONS OF ZERO GRAVITY | 2008 |
|
RU2360958C1 |
Authors
Dates
2009-05-20—Published
2008-04-07—Filed