ESTIMATE OF DISEASE SEVERITY AND INDICATIONS FOR ANTIOXIDANT THERAPY IN PATIENTS SUFFERING FROM CHRONIC CEREBRAL ISCHEMIA Russian patent published in 2009 - IPC G01N33/50 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, specifically to neurology, pathonomy, clinical pathophysiology. Estimate of disease severity and indications for antioxidant therapy in the patients suffering from chronic cerebral ischemia is ensured as follows. Blood plasma dissolved in standard buffer 1:20-1:50 is oxidised with aqueous solution CuSO₄·5H₂O with CuSO₄ concentrated as 10-20 mcmole. 4 and 24 hours after incubation at 37°C, stored products reacting with thiobarbituric acid are registered in conversion to 1 ml of undiluted plasma. The values exceeding 70 nmoles/ml and 100 nmoles/ml respectively show high risk of complicated clinical course of CCI with additional antioxidant therapy required.

EFFECT: application of the invention allows registering the processes receding functional and morphological cerebral changes and prescribing the required therapy.

6 dwg, 10 tbl, 1 ex