FIELD: chemistry.
SUBSTANCE: invention refers to Clopidogrel process by optical separation of its racemic form with using optically active amine of formula V to make optically active form of compound of formula III or its acid-additive salt followed with methylation of compound III or its salts. The intermediate product of formula resulted from reaction of racemic form of Clopidogrel and amine V.
EFFECT: possibility to make a high-yield end product.
22 cl, 12 ex
Authors
Dates
2009-06-10—Published
2005-11-28—Filed