FIELD: medicine.
SUBSTANCE: peptide is obtained from phage peptide library including set of static peptides with length of 12 aminoacid residues, by affine selection of phage clones containing peptide capable of specific linking to antibodies of benzo[α]pyrene and benzo[α]anthracene. Peptide displays specific interaction effect on antibodies of benzo[α]pyrene and benzo[α]anthracene and features molecular weight of 1.3 kDa and registered aminoacid sequence LHLPHHDGVGWG encoded by nucleotide sequence SEQ ID NO:1.
EFFECT: application in medicine as a base for peptide medicine development for immunologic prevention of malignant tumours of humans.
4 dwg, 3 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR QUANTITATIVE DETERMINATION OF ANTIBODIES TO BENZO[A]PYRENE IN HUMAN BIOLOGICAL FLUIDS | 2018 |
|
RU2702900C1 |
METHOD FOR IMMUNOENZYMOMETRIC ANALYSIS OF IDIOTYPIC AND ANTI-IDIOTYPIC ANTIBODIES TO BENZO[A]PYRENE IN HUMAN BIOLOGICAL FLUIDS | 2019 |
|
RU2741382C1 |
PEPTIDE-SIMULATOR OF HUMAN IMMUNODEFICIENCY TYPE-1 VIRUS PROTEIN GP41 CONSERVATIVE EPITOPE RECOGNIZED BY VIRUS-NEUTRALIZING MONOCLONAL ANTIBODY 2F5 (VARIANTS) | 2000 |
|
RU2179980C2 |
RECOMBINANT FRAGMID DNA pHEN-TAB CONTAINING HUMAN SINGLE-STRAND ANTIBODY GENE, CAPABLE OF BINDING OF HUMAN TUMOR NECROSIS FACTOR ALPHA; RECOMBINANT Escherichia coli BACTERIA STRAIN AS PRODUCER OF HUMAN SINGLE-STRAND ANTIBODY AGAINST HUMAN TUMOR NECROSIS FACTOR ALPHA; RECOMBINANT SOLUBLE HUMAN SINGLE-STRAND ANTIBODY AGAINST HUMAN TUMOR NECROSIS FACTOR ALPHA | 2005 |
|
RU2307163C2 |
PEPTIDE-SIMULATOR OF PROTEIN GP120 HIV-1 EPITOPE | 2000 |
|
RU2184780C2 |
ANTIIDIOTYPICAL ANTIBODY FOR ANTIBODIES INHIBITING IMMUNOGLOBULIN BONDING TO ITS HIGH AFFINITY RECEPTOR | 2000 |
|
RU2253655C2 |
TUMOR-TARGETED PEPTIDE | 2003 |
|
RU2265027C2 |
TUMOR-TARGETED PEPTIDE | 2004 |
|
RU2273644C2 |
PEPTIDE THAT SPECIFICALLY INTERACTS WITH THE HUMAN IMMUNE RESPONSE CONTROL MOLECULE B7-2 (CD86) | 2022 |
|
RU2808419C1 |
ANTIBODIES RAISED AGAINST α-INTERFERON | 2002 |
|
RU2314317C2 |
Authors
Dates
2009-06-10—Published
2007-12-03—Filed