TUMOR-TARGETED PEPTIDE Russian patent published in 2006 - IPC C07K7/08 

Abstract RU 2273644 C2

FIELD: biotechnology, medicine, oncology.

SUBSTANCE: invention relates to peptides found by selection of phage peptide library by a feature for selective binding with target-cells. These peptides are able to accumulate in lung adenocarcinoma cells and show the following amino acid sequences: RNVPPIFNDVYWIAF, SVAILPRSFSPFXVG, PFARAPVEHHDVVGL. New tumor-targeted peptides allow carrying out the purposeful delivery of preparation of different designation to lung adenocarcinoma cells. Invention can be used in medicine in treatment and diagnosis of lung adenocarcinoma and its metastasis.

EFFECT: valuable medicinal properties of peptides.

2 dwg, 2 ex

Similar patents RU2273644C2

Title Year Author Number
TUMOR-TARGETED PEPTIDE 2003
  • Nekrasov B.G.
  • Kuvshinov V.N.
  • Ushakova T.A.
  • Kaledin V.I.
  • Nikolin V.P.
  • Tumanova O.Ju.
  • Il'Ichev A.A.
  • Sandakhchiev L.S.
RU2265027C2
TUMOUR-SPECIFIC PEPTIDE FOR ADDRESS CHEMOTHERAPY OF HUMAN BREAST CANCER 2015
  • Vaskova Anna Andreevna
  • Kuligina Elena Vladimirovna
  • Makartsova Anna Aleksandrovna
  • Koval Olga Aleksandrovna
  • Rikhter Vladimir Aleksandrovich
RU2595404C1
PEPTIDE-SIMULATOR OF PROTEIN GP120 HIV-1 EPITOPE 2000
  • Tumanova O.Ju.
  • Kuvshinov V.N.
  • Nekrasov B.G.
  • Mikhajlova V.K.
  • Il'Ichev A.A.
  • Sandakhchiev L.S.
RU2184780C2
PEPTIDE-SIMULATOR OF HUMAN IMMUNODEFICIENCY TYPE-1 VIRUS PROTEIN GP41 CONSERVATIVE EPITOPE RECOGNIZED BY VIRUS-NEUTRALIZING MONOCLONAL ANTIBODY 2F5 (VARIANTS) 2000
  • Tumanova O.Ju.
  • Kuvshinov V.N.
  • Melamed N.V.
  • Ushakova T.A.
  • Masharskij A.Eh.
  • Il'Ichev A.A.
  • Klimov N.A.
  • Kozlov A.P.
  • Sandakhchiev L.S.
RU2179980C2
IMMUNOMIMETIC PEPTIDE OF CHEMICAL CANCEROGENS WITH SPECIFIC INTERACTION EFFECT ON ANTIBODIES OF BENZO[α]PYRENE AND BENZO[α]ANTHRACENE 2007
  • Glushkov Andrej Nikolaevich
  • Apal'Ko Svetlana Vjacheslavovna
  • Filipenko Maksim Leonidovich
  • Matveeva Vera Aleksandrovna
  • Khrapov Evgenij Aleksandrovich
  • Kostjanko Mikhail Vladimirovich
RU2357975C1
NEW ANTIBODY SHOWING SPECIFICITY TO MALIGNANT LARGE INTESTINE TUMOR 2001
  • Brodin Tomas N.
  • Karl'Strem Pia J.
  • Nil'Son Bo Kh. K.
  • Ol'Sson Lennart G.
  • Tordsson M. Esper
RU2268068C2
AGENT FOR NEUTRALISING SMALLPOX VIRUS 2013
  • Khlusevich Jana Aleksandrovna
  • Tikunova Nina Viktorovna
  • Morozova Vera Vital'Evna
  • Bulychev Leonid Egorovich
  • Bormotov Nikolaj Ivanovich
  • Vlasov Valentin Viktorovich
  • Sergeev Aleksandr Nikolaevich
RU2515905C1
RECOMBINANT FRAGMID DNA pHEN-TAB CONTAINING HUMAN SINGLE-STRAND ANTIBODY GENE, CAPABLE OF BINDING OF HUMAN TUMOR NECROSIS FACTOR ALPHA; RECOMBINANT Escherichia coli BACTERIA STRAIN AS PRODUCER OF HUMAN SINGLE-STRAND ANTIBODY AGAINST HUMAN TUMOR NECROSIS FACTOR ALPHA; RECOMBINANT SOLUBLE HUMAN SINGLE-STRAND ANTIBODY AGAINST HUMAN TUMOR NECROSIS FACTOR ALPHA 2005
  • Batanova Tat'Jana Aleksandrovna
  • Tikunova Nina Viktorovna
  • Jun Tat'Jana Ehverestovna
RU2307163C2
ANTIBODY RAISED AGAINST TO HUMAN GASTROENTERIC TRACT EPITHELIAL TUMOR ANTIGEN RELATED WITH ALPHA-6,BETA-4-INTEGRIN 2000
  • Brodin Tomas N.
  • Karlstrem Pia J.
  • Ol'Sson Lennart G.
  • Tordsson M. Jesper
  • Kerni Fillip P.
  • Nil'Son Bo Kh.K.
RU2266298C2
SINGLE-DOMAIN MINI-ANTIBODY aHER2/aSKBR3-1, SPECIFICALLY BINDING EPIDERMAL GROWTH FACTOR RECEPTOR HER2/ERBB2/neu AND CAPABLE TO PENETRATE THROUGH THIS INTERACTION INTO TARGET CELLS (INTERNALISED), METHOD OF PRODUCTION OF THIS ANTIBODY AND METHOD OF DETECTION OF PROTEIN HER2/ERBB2/neu AND CELLS EXPRESSING THIS PROTEIN IN INCREASED AMOUNT, USING MINI-ANTIBODY aHER2/aSKBR3-1 2012
  • Tillib Sergej Vladimirovich
  • Ivanova Tat'Jana Il'Inichna
  • Vasil'Ev Lev Anatol'Evich
  • Deev Sergej Mikhajlovich
  • Zdobnova Tat'Jana Aleksandrovna
  • Zagajnova Elena Vadimovna
RU2522929C2

RU 2 273 644 C2

Authors

Nekrasov Boris Gennad'Evich

Kuvshinov Viktor Nikolaevich

Ushakova Tat'Jana Aleksandrovna

Kaledin Vasilij Ivanovich

Nikolin Valerij Petrovich

Tumanova Ol'Ga Jur'Evna

Il'Ichev Aleksandr Alekseevich

Sandakhchiev Lev Stepanovich

Dates

2006-04-10Published

2004-04-19Filed