FIELD: biotechnologies.
SUBSTANCE: there described is the obtained and purified new protein called aflatoxin-detoxifizyme (ADTZ), which has activity of conversion of aflatoxin into non-toxic. There found is the gene coding ADTZ, as well as recombinant expression vector. There described is the transformant obtained by transforming a host cell using the above recombinant expression vector. There developed is the method for obtaining detoxifizyme, which provides for cultivation of the above transformant, obtaining, purification and reduction of expression detoxifizyme with activity of conversion of aflatoxin into non-toxic.
EFFECT: obtaining new protein that can be used for producing fodders and food products.
8 cl, 14 dwg, 12 ex
| Title |
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|
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|
RU2177480C2 |
