SUPPOSITORY FOR TUBERCULOSIS TREATMENT Russian patent published in 2009 - IPC A61K31/706 A61K31/455 A61K9/02 A61P31/06 

Abstract RU 2363474 C2

FIELD: medicine.

SUBSTANCE: invention concerns medicine, namely to the agents possessing bacteriostatic property concerning micobacteria of tuberculosis and used in phthisiology. A suppository for tuberculosis treatment contains 1-isonicotinyl-2-glucosylhydrazone dihydrate (isoglucosyl), nipagin and a base in the quantities specified in the formula of the invention. The suppository contains WITEPSOL N-15 or GHM-5T ("Supporin M") as a base. Creation of a new medicinal form - isoglucosyl suppository allows dilating assortment of antituberculous medical products, enlarges bioavailability of an agent, excludes its negative influence on gastric mucosa and duodenum and does not cause pathological disturbances of liver in comparison with peroral medicinal forms.

EFFECT: creation of a new medicinal form - isoglucosyl suppository allows to dilate assortment of antituberculous medical products, enlarges bioavailability of an agent, excludes its negative influence on gastric mucosa and duodenum and does not cause pathological disturbances of liver in comparison with peroral medicinal forms.

4 cl, 4 dwg

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RU 2 363 474 C2

Authors

Avtina Natal'Ja Valer'Evna

Kupreev Nikolaj Iosifovich

Pankrusheva Tat'Jana Aleksandrovna

Dates

2009-08-10Published

2007-07-05Filed