WAY OF ESTIMATION OF SYNERGISTIC ACTION OF GLUCOCORTICOIDS AND INTERLEUKIN-7 ON FUNCTIONAL MATURING OF T-LYMPHOCYTES OF NEWBORNS Russian patent published in 2009 - IPC G01N33/53 

Abstract RU 2363954 C2

FIELD: medicine.

SUBSTANCE: invention concerns medicine, in particular to immunology, and concerns the way of estimation of joint action of glucocorticoids and intrleukin-7 on functional maturing of T-lymphocytes of newborns. The way consists in stimulation of T-lymphocytes maturing process in a cell culture with glucocorticoids and interleukin-7 with the subsequent calculation of the synergistic action index of glucocorticoids and interleukin-7 as relation of T-cells quantity producing interferon in cell cultures with antibodies, interleukin-7 and glucocorticoids added to quantity of interferon producers in cell cultures where only antibodies and interleukin-7 are added; and at value of the index more than 1.0, - conclusion about stimulation of functional maturing of T-lymphocytes under the influence of glucocorticoids and interleukin-7 is made.

EFFECT: possibility to carry out fundamental and clinical researches of specific mechanisms regulating aging of T-lymphocytes of newborns.

2 dwg, 2 ex

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RU 2 363 954 C2

Authors

Talaev Vladimir Jur'Evich

Zaichenko Irina Evgen'Evna

Babajkina Ol'Ga Nikolaevna

Lomunova Marija Andreevna

Dates

2009-08-10Published

2007-05-30Filed