FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to occupational diseases, and can be used for correction of immune alterations in persons being in contact with toxic substances. The method is carried out as follows. Introduction of immunostimulant Cyclopheron is preceded with individual adverse effect test by incubation in vitro of Cyclopheron and mononuclear cells separated from peripheral blood. Cyclopheron is introduced provided CD19+ B-lymphocyte count is exceeded by 20% and more, and activated HLA-DR+ lymphocyte count by 15% and more.
EFFECT: method allows improving effectiveness of correction of immune alterations owing to prediction of body's immune response to Cyclopheron therapy.
1 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR ACTIVATING CYTOTOXIC T-LYMPHOCYTES IN A POPULATION OF BLOOD MONONUCLEAR CELLS USING MEMBRANE VESICLES OBTAINED FROM GENETICALLY MODIFIED TUMOR CELLS OF M14 MELANOMA WITH OVEREXPRESSION OF INTERLEUKIN 2 | 2022 |
|
RU2790867C1 |
| PROTEIN-PEPTIDE ANTITUMOR COMPOSITION, CELL PREPARATION ACTIVATED THEREWITH AND METHOD FOR TUMOR PROPHYLAXIS OR TREATMENT | 2004 |
|
RU2283129C1 |
| METHOD FOR PREDICTING OUTCOME OF SEVERE INTOXICATION WITH PSYCHOACTIVE SUBSTANCES (PAS) | 2023 |
|
RU2824425C1 |
| IMMUNOTHERAPY OF BREAST CANCER USING ANTIGEN-ACTIVATED DENDRITIC CELLS | 2016 |
|
RU2645464C1 |
| AGENT FOR TREATMENT OF PATIENTS WITH IMMUNODEFICIENCY STATE | 1999 |
|
RU2157234C1 |
| AGENT FOR TREATMENT OF PATIENTS WITH IMMUNODEFICINCY STATE | 1999 |
|
RU2157235C1 |
| METHOD OF TREATMENT OF PATIENT WITH BACTERIAL INFECTION | 1998 |
|
RU2147238C1 |
| METHOD OF IMMUNOTHERAPY MALIGNANT TUMORS OF BRAIN | 2018 |
|
RU2686756C1 |
| METHOD FOR PREPARING AUTOLOGOUS TUBERCULOSIS VACCINE | 2008 |
|
RU2372936C1 |
| METHOD FOR OBTAINING UNDIFFERENTIATED CELL | 1996 |
|
RU2215539C2 |
