FIELD: biotechnologies.
SUBSTANCE: invention relates to field of biotechnology, medicine and cellular biology. Claimed is method of differentiation of monocytic pre-cursors of dendritic cells into immature dendritic cells, as well as method of producing mature dendritic cells using colony-stimulating factor of granulocytes - macrophages GM-CSF without other cytokines under conditions which prevent cell adhesion to reservoir.
EFFECT: invention can be applied in immunotherapy based on dendritic cells, for instance, for application in treatment of diseases, including cancer.
22 cl, 15 dwg, 1 tbl, 7 ex
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