FIELD: medicine.
SUBSTANCE: invention concerns medicine, infectious diseases and can be used for plague treatment in experiment. Method involves introduction to white mice of Streptomycin 2-2.5 mg as an antibiotic and Immunofan 0.2-0.3 mkg as an immunomodulator combined in the same syringe, in 72-76 hours after contamination with high-virulent strain Y.pestis 461 in a dose 1000000-200000 "м.к." in amount 0.1-0.3 ml of dissolver.
EFFECT: application of the invention allows improving clinical effectiveness of late-staged plague, providing eradication of the agent ensured by combined introduction of Streptomycin and Immunofan.
1 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PROGNOSTICATION OF CLINICAL EFFECTIVENESS OF ANTIBACTERIAL, VACCINE PREPARATIONS, AGENTS FOR PASSIVE ANTITOXIC IMMUNOTHERAPY ON MODEL OF INFECTIOUS-TOXIC PLAGUE FORM IN MICE | 2005 |
|
RU2303821C2 |
| METHOD OF SELECTION OF WHITE MICE AND GOLDEN HAMSTERS FOR MODELLING OF EXPERIMENTAL PLAGUE INFECTION | 2007 |
|
RU2335766C1 |
| METHOD OF DETERMINATION OF FOODSTUFF CONTAMINATION WITH PATHOGENIC BIOLOGICAL AGENTS IN EXTREME SITUATIONS | 2006 |
|
RU2350656C2 |
| METHOD OF ISOLATION OF SECRETION INHIBITOR OF SIDEROPHORES SYNTHESISED BY PGMSTRAINS Y. pestis AND ISOLATED INHIBITOR | 2013 |
|
RU2549712C1 |
| STRAIN OF BACTERIUM YERSINIA PESTIS USED AS TEST-STRAIN OF CENTRAL-CAUCASUS HIGH MOUNTAINS PLAGUE LOCATION | 2006 |
|
RU2317325C1 |
| METHOD OF TOXIC SHOCK SYNDROME THERAPY AT LABORATORY ANIMALS IN CONDITONS OF EXPERIMENTAL PLAGUE | 2007 |
|
RU2336897C1 |
| METHOD FOR INCREASING IMMUNOGENIC AND PROTECTIVE ACTIVITY OF VACCINE STRAIN OF PLAGUE MICROBE | 2023 |
|
RU2815337C1 |
| METHOD OF DIFFERENTIATING STRAINS OF YERSINIA PESTIS INTO TOXICALLY ACTIVE AND INACTIVE ONES | 2017 |
|
RU2663133C1 |
| METHOD FOR INCREASING IMMUNOGENICITY OF VACCINE STRAIN OF PLAGUE MICROBE | 2019 |
|
RU2727258C1 |
| METHOD FOR DETERMINING BURKHOLDERIA MALLEI CAPSULAR ANTIGEN IMMUNOGENICITY LEVEL | 2005 |
|
RU2293993C1 |
