FIELD: medicine; veterinary science.
SUBSTANCE: selection of animals is performed on cytochemical indicators of peripheric blood and degree of full value of individuals. a condition of fermental systems, namely acidic phosphatase and cationic fibers in polymorphonuclear leucocytes of blood is used as a biochemical indicator. When content of cationic proteins totals 1.63-1.76 Keplou units with acidic phosphatase activity of 2.23-2.38 Keplou units, select white mice sensitive to the plague agent. When content of cationic proteins totals 2.05-2.15 Keplou units with acidic phosphatase activity of 1.95-2.03 Keplou units, select golden hamsters relatively resistant to plague.
EFFECT: use of the method provides high-grade selection of animals for modelling of experimental plague process and the differentiated studying of course of process at animals with different sensitivity to the agent.
1 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR EVALUATING OF DESINTOXICATION THERAPY EFFICIENCY UNDER ACTION OF TOXINS OF VARIOUS NATURE | 2007 |
|
RU2334989C1 |
| METHOD OF DIFFERENTIAL DIAGNOSIS OF BRUCELLOSIS CLINICAL FORMS IN HUMAN | 1995 |
|
RU2103687C1 |
| METHOD FOR ASSESSING IMMUNOGENICITY OF LIVE PLAGUE VACCINE USING IN VITRO ANTIGEN SPECIFIC CELLULAR TESTS | 2018 |
|
RU2680697C1 |
| METHOD OF OBTAINING HELPER FRACTIONS OF NEUTROPHILOKINS, SYNTHESIZED WITH NUERTOPHILS OF PERITONEAL EXUDATE OF EXPERIMENTAL ANIMALS UNDER IMPACT OF VACCINE STRAIN OF PLAGUE MICROBE | 2007 |
|
RU2341561C1 |
| METHOD OF PLAGUE LABORATORY DIAGNOSIS | 1993 |
|
RU2077591C1 |
| SET OF RECOMBINANT FLUORESCENT STRAINS OF YERSINIA PESTIS BACTERIA OF MAIN SUBSPECIES BIOVAR AND THE ALTAI BIOVAR OF THE CENTRAL ASIATIC SUBSPECIES FOR INDICATION OF PLAGUE AGENT IN EXPERIMENTAL SAMPLES | 2020 |
|
RU2769790C1 |
| STRAIN OF BACTERIUM YERSINIA PESTIS USED AS TEST-STRAIN OF CENTRAL-CAUCASUS HIGH MOUNTAINS PLAGUE LOCATION | 2006 |
|
RU2317325C1 |
| METHOD FOR DETERMINING BURKHOLDERIA MALLEI CAPSULAR ANTIGEN IMMUNOGENICITY LEVEL | 2005 |
|
RU2293993C1 |
| STRAIN OF BACTERIUM YERSINIA PESTIS USED AS TEST-STRAIN RESISTANT TO PLAGUE BACTERIOPHAGE L-413 "C" | 2000 |
|
RU2203316C2 |
| METHOD OF COUPLED ESTIMATION OF FUNCTIONAL ACTIVITY OF PERIPHERAL BLOOD NEUTROPHILS AT BRUCELLOSIS PATHOGEN EFFECT | 1997 |
|
RU2133471C1 |
