PYRROLOPYRIMIDINE DERIVATIVES APPLICABLE IN TREATING PROLIFERATIVE DISEASES Russian patent published in 2009 - IPC C07D487/04 A61K31/495 A61P35/00

Abstract RU 2367662 C2

FIELD: medicine.

SUBSTANCE: invention refers to new compounds of formula I where R¹ stands for phenyl; G stands for C₁-C₇-alkylene; Q stands for -NH-; and X stands for C₁-C₇- alkylene, or to its salts. In addition, the invention concerns a pharmaceutical composition, to application of compound of formula I as defined in claims 1-5 item, as well as the method for making the compound of formula I.

EFFECT: production of the new biologically active compounds inhibiting protein tyrosine kinase.

8 cl, 3 ex

Similar patents RU2367662C2

Title	Year	Author	Number
COMBINATIONS CONTAINING TRANSDUCTION SIGNAL INHIBITOR AND EPOTILONE DERIVATIVE	2002	Brandt Ral'F Bukhdunger Ehlizabet Khel'Din Karl-Khenrik Estman Arne Pitras Kristian O`Rejli Terens Rotermel Dzhon Dejvid Traksler Peter Vartmann Markus	RU2313345C2
COMBINATION CONTAINING IRON COMPLEX AND ANTINEOPLASTIC AGENT, AND USE THEREOF	2007	Nikk Khanspeter	RU2469721C2
COMBINATIONS CONTAINING EPOTHILONES AND PROTEIN KINASE INHIBITORS AND PHARMACEUTICAL APPLICATION THEREOF	2005	Khuan Dzherri Min'Tszjan' Dzhori Anandkhi Ranganatan Linnartts Ronald Richard Makshini Pol M. Dzh.	RU2423980C2
METHOD FOR TREATING PROLIFERATIVE DISORDERS AND OTHER PATHOLOGICAL CONDITIONS MEDIATED BY ACTIVITY OF KINASE BCR-ABL, C-KIT, DDR1, DDR2 OR PDGF-R	2010	Nil Gallager Ofeliya In	RU2625835C2
DERIVATIVES OF ISOTHIOUREA AND METHOD OF THEIR PRODUCTION, THEIR APPLICATION AND PHARMACEUTICAL COMPOSITION	2005	Glikman Frejser Shtrajff Markus Toma Gebkhard Tserves Khans-Gjunter	RU2376297C2
COMBINATIONS CONTAININS Bcr-Abl/c-Kit/PDGF-RTK INHIBITORS FOR TREATING CANCER	2007	Berk Gregori Piter Linnartts Ronald Richard Manli Pol U. Versejs Richard Uill'Jam	RU2452492C2
DERIVATIVES OF 4-AMINO-6-PHENYLPYRROLO[2,3]PYRIMIDINE POSSESSING INHIBITORY EFFECT ON TYROSINE KINASE ACTIVITY, THEIR USING AND METHODS FOR THEIR PREPARING (VARIANTS)	2002	Bol'D Guido Kapraro Khans-Georg Karavatti Dzhordzho Traksler Peter	RU2318826C2
4-AMINO-5-PHENYL-7-CYCLOBUTYLPYRROLO[2,3-D]PYRIMIDINE DERIVATIVES	2002	Kapraro Khans-Georg Fjure Paskal' Garsija-Ehcheverrija Karlos Manli Pol Uill'Jam	RU2305682C2
COMBINATIONS CONTAINING ANTIDIARRHEAL AGENT AND EPOTHYLON OR EPOTHYLON DERIVATIVES	2002	Rotermel Dzhon Dejvid Shran Khorst F. Grili Diana Tjan'Lin Chehn' Tjan'Lin	RU2330661C2
COMBINATIONS OF ACTIVATOR (ACTIVATORS) OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR), AND INHIBITOR (INHIBITORS) OF STEROL ABSORPTION AND TREATMENT OF VASCULAR DISEASES	2008	Kosoglou Teddi Dehvis Garri R. Pikar Zhill' Zhan Bernar Sho Ving-Ki Filip	RU2483724C2

RU 2 367 662 C2

Authors

Karavatti Dzhordzho

Traksler Peter

Ehsser Tomas

Khe Khandan

Dates

2009-09-20—Published

2005-01-28—Filed