OLIGOCHITOSAN COMPLEX SALT AND METHOD OF OBTAINING SAID SALT Russian patent published in 2009 - IPC C08B37/08 A61K31/722 

Abstract RU 2369618 C1

FIELD: chemistry.

SUBSTANCE: complex salt of chitosan oligomers has viscosity-average molecular weight from 1600 to 2100 Da and the following molecular-mass distribution of chitosan oligomer homologues: from 20 to 25% chitosan oligomer homologues, containing 2 to 6 repeating D-glucosamine residues; from 64 to 72% chitosan oligomer homologues, containing 7 to 12 repeating D-glucosamine residues; from 8 to 16% chitosan oligomer homologues, containing 13 to 20 repeating D-glucosamine residues. Method of obtaining the said complex salt involves formation of a chitosan solution in an aqueous solution of at least one organic acid, taken in stoichiometric amount of 23 to 115%, addition of enzymes to the obtained chitosan solution and enzymic hydrolysis of the chitosan solution until achieving dynamic viscosity of the reaction mixture, equal to 1.60-1.80 cP with formation of the end product in the solution, which is then concentrated and dried.

EFFECT: improved method of obtaining oligochitosan salts.

7 cl, 12 ex

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Authors

Frolov Vadim Gennad'Evich

Nistratov Vjacheslav Petrovich

Smirnova Larisa Aleksandrovna

Alekseeva Majja Fedorovna

Dates

2009-10-10Published

2008-05-22Filed