COMPOSITIONS OF PARTIALLY DEACETYLATED CHITIN DERIVATIVES Russian patent published in 2011 - IPC C08B37/08 A61K31/722 A61P19/02 A61K9/00 

FIELD: medicine.

SUBSTANCE: method for the recovery of high-purity and completely soluble partially deacetylated chitin polymer of deacetylation degree (DD) 30-60 % involves the stages: neutralisation of partially deacetylated chitin; dissolution of partially deacetylated chitin in an acid; removal of undissolved particles by sequential filtration stages; pH reduction of the solution to 8 and more; precipitation of completely dissolved and purified partially deacetylated chitin by temperature rise and salt addition where the precipitate is removed and rinsed after precipitation by filtration or centrifugation and where rinsing water and deposit temperature is 40°C and higher. Also the invention refers to a neogenesis composition containing therapeutically active N-acetylglucosamine (A) and glucosamine (D) chitooligomers where the composition contains heterochitooligomers which shall meet the following criteria: said oligomers have a chain length in the range 5-20 monomer residues; each oligomer chain can have two residues of N-acetyl-D-glucosamine (AA) on any or both ends of the oligomer chain, the remained inside of the oligomer has a maximum number of the residues A; the sequence of said inside of the chain is such that the N-acetyl-D-glucosamine residue (A) does not adjoin to the other N-acetyl-D-glucosamine (A) residue (such as, e.g. AA).

EFFECT: biomaterial based on said compositions intensifies the bone repair and hemostasis in healing of a fractured or seriously injured bone.

21 cl, 32 dwg, 9 tbl, 9 ex