FIELD: medicine.
SUBSTANCE: invention concerns medications, particularly self-emulsifying system of butylphthalide drug delivery, including 1% to 65% of butylphthalide, 10% to 65% of emulsifying agent, and filler. Emulsifying agent is a mix of polyoxyetylene castor oil and polyethyleneglycol-8-glycerin caprilate/caprate, where polyoxyethylene castor oil to polyethyleneglycol-8-glycerin caprilate/caprate ratio is 1:0.5 to 1:1.5. Invention also concerns medication containing claimed delivery system, and method of system obtainment.
EFFECT: faster achievement of maximum butylphthalide concentration, increased maximum concentration, improved butylphthalide stability.
9 cl, 1 dwg, 3 tbl, 18 ex
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