COMPLEX PROBIOTIC MEDICINE IN IMMOBILISED AND LYOPHILISED FORM Russian patent published in 2009 - IPC C12N11/00 A61K35/74 

Abstract RU 2371479 C1

FIELD: medicine.

SUBSTANCE: invention concerns medical and veterinary drugs and methods of their obtainment and can be applied in biotechnology, medicine and agriculture. Complex probiotic medicine includes carrier in the form of porous enterosorbent, and eubiotic bacteria cells with nutrient and protective media, immobilised at the enterosorbent. Eubiotic bacteria cells with nutrient medium comprise lyophilised concentrate of bifidobacteria or lactobacteria consortium, or their mix with the titre of 108-1010 colony forming units per gram. Carbon enterosorbent VNIITU-1 or 2 of All-Russian Scientific Research Institute of Carbon Black is used as porous enterosorbent, at the following dry medicine component ratio, wt %: cells of eubiotic bifido- or lactobacteria consortium, or their mix of 108-1010 colony forming units per gram titre, with nutrient medium - 1.0-15.0, protective medium - 0.1 - 10.0, carbon enterosorbent VNIITU-1 or 2 - the rest to 100%. Bifido- and lactobacterium consortiums are mixed at the ratio of 1:1 to 3:1.

EFFECT: higher bacterium cell sorption and desorption efficiency by enterosorbent, enhancing clinical effect, and higher colony forming activity of eubiotic bacteria.

5 cl, 2 tbl, 5 ex

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Authors

Molokeev Aleksej Vladimirovich

Il'Ina Roma Miroslavovna

Jatsentjuk Raisa Mikhajlovna

Molokeeva Natal'Ja Valentinovna

Zykova Natal'Ja Al'Gimantasovna

Karikh Tat'Jana Leonidovna

Sokolova Tat'Jana Vasil'Evna

Nikulin Leonid Georgievich

Kuslij Aleksandr Georgievich

Mironenko Vjacheslav Vladimirovich

Jasudis Galina Vladimirovna

Guseva Irina Aleksandrovna

Dates

2009-10-27Published

2008-02-12Filed