FIELD: chemistry.
SUBSTANCE: new method is described for producing new derivatives in the series 5-amino-2,4-dihydro-3N-1,2,4-triazole-3-thiones, and specifically to a method of producing 4,5-disubstituted 2,4-dihydro-3N-1,2,4-triazole-3-thiones with general formula I: 
, where R1=C1-C6 alkylphenyl, haloid phenyl, thienyl, furanyl or pyrrolyl; R2= phenyl C1-C6 alkyl, naphthyl C1-C6 alkyl, anthryl C1-C6 alkyl, C1-C6 alkoxyphenyl, which involves reaction of corresponding acylisothiocyanates, obtained from acylchlorides R1-C(O)Cl and ammonium rhodanide, with 4-R2- thiosemicarbazides R2-NH-C(S)-NH-NH2 and subsequent cyclisation of N-[2-(R2- carbamothioyl) hydrazinocarbonothioyl]acylamides in a medium of high-boiling aliphatic alcohols.
EFFECT: desired product, which is obtained with high output and purity, can be used in medicine.
1 cl, 8 ex
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