FIELD: chemistry.
SUBSTANCE: invention relates to an improved method of producing N,N,N,N-tetramethylalkadiynediamines, which can be used in fine organic synthesis, particularly for producing not easily accessible polycyclic compounds, as well as in synthesis of biologically active substances. Desired compounds are obtained from reacting diacetylene alkanes with excess N,N,N,N-tetramethylmethane diamine in the presence of a vanadyl acetylacetonate (VO(acac)2) catalyst, in molar ratio diacetylene alkane: N,N,N,N-tetramethylmethane diamine: VO(acac)2 = 10:(25-35):(0.2-0.4) in an argon atmosphere at temperature ranging from 70 to 100°C, mostly at 80°C, and atmospheric pressure for 4 to 8 hours.
EFFECT: method considerably simplifies synthesis schematic due to use of accessible initial reagents and significantly increases output of desired products, and allows for obtaining new and known compounds.
1 cl, 3 dwg, 1 tbl, 1 ex
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