FIELD: chemistry.
SUBSTANCE: proposed invention pertains to organic chemistry, more specifically to the method of producing N,N-dimethyl-3-phenyl-2-propyne-1-amine. The method involves reacting phenylacetylene with excess bisamine in the presence of a vanadyl acetylacetonate catalyst (VO(acac)2) in an argon atmosphere at 85°C temperature and atmospheric pressure for a period of 4-8 hours. N,N-dimethyl-3-phenyl-2-propyne-1-amine output is 84-98%.
EFFECT: invention can be used in thin organic synthesis, particularly for making not easily accessible polycyclic compounds, as well as in synthesis of biologically active substances.
1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING N,N,N,N-TETRAMETHYLALKADIYNEDIAMINES | 2007 |
|
RU2373189C2 |
| METHOD OF PRODUCING N,N,N,N-TETRAMETHYL-2-BUTYNE-1,4-DIAMINE | 2010 |
|
RU2448951C2 |
| METHOD OF PRODUCING N,N,N,N-TETRAMETHYL-2-BUTYNE-1,4-DIAMINE | 2008 |
|
RU2408572C2 |
| METHOD OF PRODUCING N,N,N,N-TETRAMETHYL-2-BUTENE-1,4-DIAMINE | 2008 |
|
RU2440329C2 |
| 4-(DIMETHYLAMINO)-1-ALKYL-1-METHYL-2-ALKYN-1-OLS SYNTHESIS METHOD | 2008 |
|
RU2378249C2 |
| CATALYST FOR SYNTHESIS OF 1-(DIMETHYLAMINO)-3-ALKYL-2-PROPINES | 2008 |
|
RU2399413C2 |
| METHOD FOR SYNTHESIS OF 1-AMINOMETHYL-2-PHENYLACETYLENES | 2008 |
|
RU2391335C2 |
| METHOD OF PRODUCING 4-(DIMETHYLAMINO)-2-BUTINYL ALKANOATES | 2008 |
|
RU2436766C2 |
| METHOD FOR SYNTHESIS OF ASYMMETRIC (-DI(AMINOMETHYL)ALKADIINES | 2009 |
|
RU2409544C2 |
| METHOD FOR PREPARATION OF 1-(2-ALKYNYL)PIPERIDINES | 2008 |
|
RU2367657C1 |
