FIELD: chemistry.
SUBSTANCE: invention relates to an improved method of producing N1,N1,N4,N4-tetramethyl-2-butyne-1,4-diamine, which is used in synthesis of polycyclic compounds, as well as in synthesis of biologically active substances. The method involves reaction of N,N,N,N-tetramethylmethane-diamine with excess gaseous acetylene in the presence of a VO(acac)2 catalyst, taken in molar ratio of N,N,N,N-tetramethylmethane-diamine: (VO(acac)2) = 10 : (0.3-0.5), preferably 10:0.4, at temperature 65-75°C and atmospheric pressure for 1-3 hours.
EFFECT: method increases output of the desired product.
1 cl, 3 dwg, 1 tbl, 1 ex
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