PYRROLOTRIAZINE COMPOUNDS AS KINASE INHIBITORS Russian patent published in 2009 - IPC C07D487/04 A61K31/53 A61P35/00 

Abstract RU 2373209 C2

FIELD: chemistry.

SUBSTANCE: new pyrrolotriazine derivatives of general formula (I) are described, where R1 is possibly substituted piperidinyl or piperazinyl; R2 is possibly substituted phenyl; R3 is hydrogen; X is -NH-; Y is -CH2-; as well as their pharmaceutically acceptable salts or steroisomers, and pharmaceutical compositions containing said compounds.

EFFECT: given compounds are kinase inhibitors and can be used in medicine, for example as anticancer agents.

9 cl, 267 ex, 2 dwg

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RU 2 373 209 C2

Authors

Fink Brajan E.

Gavaj Ashvinikumar V.

Vit Gregori D.

Chen Ping

Mastehlerz Khehrold

Norris Derek Dzh.

Tokarski Dzhon S.

Zhao Jufen

Khan Ven-Ching

Dates

2009-11-20Published

2004-12-23Filed