THERAPEUTIC AND DIAGNOSTIC DRUG AND BIOLOGICALLY ACTIVE SUBSTANCE CARRIER AND APPLICATION THEREOF FOR MAKING DRUGS AND METHOD OF REGULATED CONTROLLED DRUG OR BIOLOGICALLY ACTIVE SUBSTANCE DELIVERY WITH REGULATED DESORPTION Russian patent published in 2009 - IPC A61K47/36 A61K47/34 A61K47/02 A61K9/62 A61K9/58 A61K9/52 A61K9/18 A61K49/18 A61K49/12 A61M31/00 A61M37/00 B82B3/00 

Abstract RU 2373957 C2

FIELD: medicine.

SUBSTANCE: invention refers to a carrier for drugs, biologically active substances, biological objects used in medicine for diagnostics and treatment in pharmaceutical industry. The carrier represents a material sensitive to external magnetic or electric fields and consisting of magnetic or ferroelectric material filmed with biocompatible thermosensitive, biodegradable polymer and/or dispersed in thermosensitive medium properties of which change with varying temperature relative to that of human body within 15.9 to 42°C. The magnetic or ferroelectric materials are made of substance with great magnetocaloric or electrocaloric component effect 1 to 13 K, have temperature of magnetic or ferroelectric phase transition within temperature range 33 to 37°C, and are chosen from the group including rare-earth, transition and precious metals, their alloys and compounds.

EFFECT: invention also concerns methods of controlled drug delivery by means of such carrier with enabling release thereof (regulated desorption) in the preset point.

32 cl, 9 ex

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RU 2 373 957 C2

Authors

Tishin Aleksandr Mettalinovich

Rochev Jurij Alekseevich

Gorelov Aleksandr Vladimirovich

Dates

2009-11-27Published

2006-10-13Filed