FIELD: chemistry.
SUBSTANCE: description is given of oxadiazolone derivatives of formula (I) 
where X is CH2 or a bond; R1, R2, R3, R4 are independently H, F, CI, Br, CF3, (C1-C4)-alkyl, (C0)-alkylene-O-(C1-C4)-alkylene-H, SCH3, S(O)CH3, S(O)2CH3, CN; Z is a bond or CH2; Y is O, S, S(O) or S(O)2; W is CH2 or CH2CH2; one of U and V is N, and the other is S or O; R5 is selected from a group which consists of (C1-C8)-alkyl, (C1-C6)-alkylene-O-(C0-C4)-alkylene-H, (C1-C6)-alkylene-O-(C0-C4)-alkylenephenyl, (C2-C8)-alkenyl, and where (C1-C8)-alkyl or alkylene can be mono- or di-substituted with OH or O-(C1-C4)-alkyl; R6, R7 are independently H, CF3, (C0-C4)-alkylene-O-(C0-C4)-alkylene-H, SF5, phenyl; and their physiologically acceptable salts.
EFFECT: obtaining new compounds which exhibit agonistic effect on PPAR-delta.
23 cl, 2 tbl, 51 ex
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