POROUS COMPOSITE MATERIALS BASED ON CHITOSAN FOR FILLING OF BONE DEFECTS Russian patent published in 2009 - IPC A61K31/722 A61K33/06 A61P19/08 

Abstract RU 2376019 C2

FIELD: medicine.

SUBSTANCE: invention is related to the field of medicine and is related to composite materials for plastic reconstruction of damaged bone tissues. Invention represents porous composite material on the basis of chitosan for filling of bone defects, which contains chitosan, tricalcium phosphate and differs by the fact that it contains chitosan with molecular weight of more than 300000 g/mole, additive of ammonium carbonate, and calcium-phosphate fillers used are substances in the form of powder or granules with particle size of 1-1000 mcm, selected from the following group: brushit, monetite, tetracalcium phosphate, hydroxyapatite, carbonate hydroxyapatite, or their mixtures, at the same time components of material are available in a certain ratio.

EFFECT: invention provides for filling of bone defects of various shape and size, and calcium-phosphate fillers contained in sponge together with chitosan create favourable conditions for formation of natural human bone tissue.

11 ex, 2 tbl, 1 dwg

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RU 2 376 019 C2

Authors

Barinov Sergej Mironovich

Smirnov Valerij Vjacheslavovich

Fedotov Aleksandr Jur'Evich

Komlev Vladimir Sergeevich

Fadeeva Inna Vilorovna

Sergeeva Natal'Ja Sergeevna

Sviridova Irina Konstantinovna

Kirsanova Valentina Aleksandrovna

Akhmedova Suraja Abdulla Kyzy

Dates

2009-12-20Published

2007-12-26Filed