COMPOSITE MATERIAL FOR FILLING BONE DEFECTS, CONTAINING AN ALGINATE-CHITOSAN POLYELECTROLYTE COMPLEX Russian patent published in 2022 - IPC A61L27/00 A61L27/12 A61L27/20 A61L27/46 C08L5/04 C04B35/447 C01B25/32 

Abstract RU 2765546 C1

FIELD: medicine.

SUBSTANCE: invention relates to the field of medicine and creation of new biomedical materials usable in creation of materials for orthopedics and traumatology. Proposed is a composite material for filling bone defects, containing a mixture of calcium phosphates, contained in the total mass whereof are: hydroxylapatite (HA) - 20%, brushite - 30%, octacalcium phosphate (OCP) - 50%, and additionally containing an alginate-chitosan polyelectrolyte complex (PEC), at the following ratio of components, wt.%: PEC 30÷50, the mixture of calcium phosphates 70÷50. PEC constitutes a mixture of 1:1 to 2% aqueous suspension of sodium alginate and 2% solution of chitosan in 0.5% acetic acid.

EFFECT: creation of a biocompatible composite material based on a mixture of calcium phosphates in the volume of an alginate-chitosan matrix.

1 cl, 2 dwg, 1 tbl

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RU 2 765 546 C1

Authors

Golovanova Olga Aleksandrovna

Tsyganova Anna Anatolevna

Dates

2022-02-01Published

2020-08-05Filed