POROUS COMPOSITE CHITOSAN AND GELATIN-BASED MATERIAL FOR FILLING IN BONE DEFECTS Russian patent published in 2011 - IPC A61K31/722 A61K33/06 A61L27/56 A61L27/12 A61L27/26 

Abstract RU 2412711 C1

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine and deals with composite materials for plastic reconstruction of damaged bone tissues. Obtained is porous composite chitosan-gelatin sponge containing octacalcium phosphate in form of powder or granules. Introduction of gelatin increases sponge plasticity, which makes it possible to fill in bone defects of various form and size, as well as increases sponge solubility.

EFFECT: octacalcium phosphate contained in sponge demonstrates osteoinductive properties, which in combination with chitosan creates favourable conditions for formation of natural human bone tissue.

1 tbl, 9 ex

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RU 2 412 711 C1

Authors

Barinov Sergej Mironovich

Komlev Vladimir Sergeevich

Fadeeva Inna Vilorovna

Fedotov Aleksandr Jur'Evich

Fomin Aleksandr Sergeevich

Dates

2011-02-27Published

2009-09-17Filed