FIELD: medicine.
SUBSTANCE: invention relates to field of medicine and deals with composite materials for plastic reconstruction of damaged bone tissues. Obtained is porous composite chitosan-gelatin sponge containing octacalcium phosphate in form of powder or granules. Introduction of gelatin increases sponge plasticity, which makes it possible to fill in bone defects of various form and size, as well as increases sponge solubility.
EFFECT: octacalcium phosphate contained in sponge demonstrates osteoinductive properties, which in combination with chitosan creates favourable conditions for formation of natural human bone tissue.
1 tbl, 9 ex
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Authors
Dates
2011-02-27—Published
2009-09-17—Filed