METHOD OF PRODUCTION OF POROUS CERAMIC GRANULES ON BASIS OF CALCIUM CARBONATE AND HYDROXYAPATITE AND/OR CARBONATE HYDROXYAPATITE FOR FILLING OF BONE DEFECTS AT RECONSTRUCTIVE PLASTIC SURGERIES Russian patent published in 2015 - IPC A61L27/02 A61L27/12 A61L27/14 C04B35/447 

FIELD: biotechnologies.

SUBSTANCE: invention offers the materials on the basis of calcium carbonate system - hydroxyapatite and/or carbonate hydroxyapatite, containing from 20 up to 80 wt % of calcium carbonate with bioactive properties and high bioresorption that favours to fast recovery of bone tissue. Granules of the named composition have been produced according to the suspension technology based on the principle of immiscible liquids as a result of dispergating of suspension on the basis of polyacrylamide solution into the medium of vegetable oil with the temperature 80-180°C. After washing and drying the produced granules have been baked in the medium of carbon dioxide at the temperature 620-700°C.

EFFECT: obtaining porous ceramic granules with the adjustable size from 100 up to 2000 mcm, open porosity and with pore size from 20 up to 400 mcm.

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